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    Mitral regurgitation, which is caused by a leaky heart valve, can place serious burdens on your quality of life. Learn more about mitral regurgitation treatment options and how the MitraClip procedure may help you. To find out more please read our Privacy and Cookies policy. The information contained in this section of the site is intended for U. Click the appropriate button below.
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    Mitral Valve Clip for Treatment of Mitral Regurgitation: An Evidence-Based Analysis

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    MitraClip Procedure | Mitral Regurgitation Treatment

    Mitral regurgitation MR is the most prevalent form of moderate or severe valve disease in developed countries. Primary or degenerative MR is caused by pathology of one or more of the components of the mitral valve MV leading to valve incompetence and subsequently to left ventricular LV remodeling and dysfunction. In contrast, secondary or functional MR is characterized by structurally normal valve leaflets and chordae in the setting of LV remodeling and dysfunction leading to an imbalance between closing and tethering forces on the valve. Medical management does not alter the outcome of MR, and current guidelines recommend surgical intervention for patients with severe symptomatic primary MR or those with high-risk features. Transcatheter valve interventions have emerged as a viable alternative for patients who are at prohibitive risk for surgery.
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    Mitral Valve Clip

    Mitral valve repair and mitral valve replacement are procedures that may be performed to treat diseases of the mitral valve — the valve located between the left heart chambers left atrium and left ventricle. Several types of mitral valve disease exist. In mitral valve regurgitation, the flaps leaflets of the mitral valve don't close tightly, causing blood to leak backward into the left atrium. This commonly occurs due to valve leaflets bulging back — a condition called mitral valve prolapse.
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    Many of the , North American patients with chronic mitral regurgitation may be poor candidates for mitral valve surgery. The objective of this study was to investigate the comparative effectiveness, harms, and cost-effectiveness of percutaneous mitral valve repair using mitral valve clips in candidates at prohibitive risk for surgery. Grey literature was also searched. Primary studies were sought from existing systematic reviews that had employed reliable search and screening methods.
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